The feeling that your body is not “running at full capacity” may not be related only to sleep or advancing age. The amount of energy we have is largely determined by mitochondria – tiny structures inside our cells that are one of the most underestimated pillars of long-term health. What exactly do they do for us, and how can we support their function?
What are mitochondria and why are they important?
You can think of mitochondria as small but powerful cellular power plants. They are found in almost every cell in the body, and their main role is to convert nutrients from food into energy in the form of the ATP molecule – the universal “fuel” for muscles, the brain, and organs.
The more energy a cell needs, the more mitochondria it usually contains. That is why muscle cells, nerve cells, and heart cells tend to have significantly more of them than other tissues.
But mitochondria are not just passive energy producers. They also help with:
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supporting proper cell function,
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protecting cells from oxidative stress,
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regulating cell renewal and the natural “recycling” of damaged structures (known as mitophagy).
So by now you may already understand that as mitochondria function, so does the whole body.
Energy today, health tomorrow
With age, stress, or long-term overload, mitochondrial function gradually declines. And that is far from ideal. Research shows that reduced mitochondrial activity goes hand in hand with:
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chronic fatigue,
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a slower metabolism,
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poorer recovery,
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reduced muscle strength,
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a higher risk of chronic disease.
It is no surprise, then, that mitochondrial dysfunction is now being discussed as one of the key mechanisms of ageing. Not because mitochondria “stop working overnight,” but because they gradually lose efficiency over time – producing less energy while generating more by-products that place strain on cells.
The good news is that mitochondria are surprisingly adaptable. Under the right conditions, they can become more efficient again and can even multiply. So nothing is lost yet.
Mitochondria thrive on the right kind of stress
One of the most interesting findings of recent years is that mitochondria respond positively to short-term, moderate stress. This principle is known as hormesis.
Examples of natural stimuli for mitochondria include:
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physical activity (especially endurance and interval training),
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short-term fasting or longer breaks between meals,
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exposure to cold or heat,
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quality sleep and respecting circadian rhythms.
These signals tell the body that it needs to produce energy more efficiently. And mitochondria respond by increasing their capacity.
NAD+: a key player in cellular energy
Longevity experts are also looking for additional ways to support mitochondrial health even more. And their research looks promising. For example, they have found that mitochondria cannot function without NAD⁺ (nicotinamide adenine dinucleotide). This coenzyme transfers electrons during energy production, activates cellular repair mechanisms, and generally supports proper mitochondrial function.
However, NAD⁺ levels naturally decline with age – some studies suggest by as much as 50% between the ages of 20 and 60. This may contribute to lower energy levels and a reduced ability to recover.
That is why science is now intensively exploring NAD⁺ precursors – substances the body can use to produce NAD⁺ on its own. One of the most established is nicotinamide riboside (NR).
Did you know…
…mitochondria also need other “building” and “fuel” substances?
In addition to NAD+, the availability of other nutrients involved in energy metabolism also plays an important role:
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Coenzyme Q10 is part of the mitochondrial respiratory chain and is directly involved in ATP production. Its levels decline with age, especially in energy-demanding – yet highly important – tissues.
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B vitamins (B1, B2, B3) are essential partners for the enzymes that convert carbohydrates, fats, and proteins into energy.
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PQQ (pyrroloquinoline quinone) is a compound studied for its potential to support the formation of new mitochondria (mitochondrial biogenesis).
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Glycine is involved in the production of glutathione – one of the main antioxidants that helps protect mitochondria from damage.
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TMG (trimethylglycine) supports natural biochemical processes in the body (including NAD⁺ metabolism) that help maintain cellular energy.
It is therefore difficult to achieve targeted mitochondrial support with a single isolated substance. For comprehensive mitochondrial care, it makes sense to choose synergistic multi-ingredient supplements, which can be a suitable complement to a healthy lifestyle.
MitoGenix combines nutrients involved in energy metabolism, mitochondrial protection, and adaptation to stress. NAD+ Prime helps increase NAD⁺ levels, which are key to cellular energy, and supports its efficient use in the body.
For metabolic balance, mitochondrial performance, and steady energy
- Stable energy throughout the day
- Supports healthy metabolism
- Supports mitochondrial vitality
- Physical recovery and resilience
- Monthly supply: 60 capsules | 30 daily servings
Advanced support for NAD⁺ and mitochondrial energy for recovery and cellular performance
- Supports NAD⁺ levels
- Supports mitochondrial energy
- Cellular vitality and regeneration
- Protection of cells from oxidative stress
- Monthly supply: 60 capsules | 30 daily servings
Energy as a long-term asset
Forget the quick “boost.” Supporting mitochondria is an investment in long-term vitality, resilience, and the body’s ability to recover. And that is where the true luxury of modern health lies: having energy not just today, but being able to rely on it tomorrow as well.
Sources:
- https://pubmed.ncbi.nlm.nih.gov/26942670/
- https://pubmed.ncbi.nlm.nih.gov/23454757/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7963035/
- https://www.mdpi.com/2072-6643/14/9/1811
- https://pubmed.ncbi.nlm.nih.gov/19861415/
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