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MitoGenix

Food supplement for mitochondrial energy, metabolic balance, and steady vitality throughout the day, 60 capsules

| 25 Total number of reviews
MitoGenix
MitoGenix
MitoGenix
MitoGenix
MitoGenix
MitoGenix

MitoGenix

Food supplement for mitochondrial energy, metabolic balance, and steady vitality throughout the day, 60 capsules

| 25 Total number of reviews

For metabolic balance, mitochondrial performance and steady energy

  • Activates AMPK - the bodyโ€™s main metabolic switch
  • Increases mitochondrial efficiency and cellular ATP energy production
  • Supports healthy sugar and fat metabolism
  • Helps increase NAD+ levels and supports cellular vitality
  • Supports autophagy and natural metabolic renewal
  • Contributes to more stable energy without sharp crashes
  • Supports physical endurance, recovery, and muscle resilience
  • Contains no caffeine or typical stimulants
  • Monthly supply: 60 capsules | 30 daily servings
  • Every NOZONO product comes in a luxurious glass jar

In stock. Ships immediately.
 
Non-GMO

Non-GMO

Gluten-free

Gluten-free

For vegans

For vegans

Free from major allergens

Free from major allergens

Endotoxin-free

Endotoxin-free

No preservatives

No preservatives

 
Reviews
About the product Key benefits Bundles Ingredients Frequently asked questions
4.9
25 reviews for this product
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MitoGenix

Stable energy starts within your cells

The feeling of energy is not just a matter of motivation or the number of cups of coffee you drink. True energy is created in the mitochondria โ€“ the cellular powerhouses that convert nutrients from food into ATP, the universal fuel for the brain, muscles, organs, recovery, and everyday performance.

NOZONO MitoGenix is a premium mitochondrial and metabolic formula designed for stable energy, efficient nutrient utilization, and long-term cellular performance.ย It does not work like a quick stimulant that briefly boosts the body and is then followed by an energy crash. Instead, it focuses directly on the processes through which the body creates and uses energy.

This thoughtfully designed formula combinesย fermented L-glycine, dihydroberberine, coenzyme Q10, PQQ, vitamins B1 and B3, and BioPerineยฎ. The individual ingredients support mitochondrial efficiency, AMPK activation, glucose and fat metabolism, autophagy, and the bodyโ€™s natural production of cellular energy.

With age, during prolonged stress, lack of sleep, or high metabolic demand, the bodyโ€™s ability to create energy efficiently may gradually decline. The result may be afternoon slumps, lower endurance, slower recovery, or the feeling that the body cannot keep up with the demands of the day.

MitoGenix supports the cellular energy system without unnecessarily overloading the nervous system. It helps the body work with energy more evenly, efficiently, and sustainably โ€“ from morning focus to evening activities.

It contains no caffeine or typical stimulant substances. It is intended for regular use by people who want more stable energy without sharp fluctuations, better metabolic resilience, and performance that lasts longer than the first half of the day.

MitoGenix does not give the body another short-term boost. It supports the place where real energy begins.

SCIENTIFIC EVIDENCE

A randomized clinical study published in the Journal of the American College of Nutrition (2020) showed that supplementation with PQQ (20 mg daily for 6 weeks) in men significantly increased levels of the PGC-1ฮฑ protein, the main regulator of new mitochondria formation, compared to placebo. PQQ thus directly stimulates mitochondrial biogenesis at the cellular level.

Study: Hwang PS et al. Effects of Pyrroloquinoline Quinone (PQQ) Supplementation on Aerobic Exercise Performance and Indices of Mitochondrial Biogenesis in Untrained Men. J Am Coll Nutr, 2020; 39(6): 547โ€“556.
Link: https://pubmed.ncbi.nlm.nih.gov/31860387/
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How MitoGenix works

MitoGenix supports key processes linked to cellular energy production, metabolic balance, and long-term vitality. Its comprehensive formula helps the body use nutrients more efficiently and create stable energy without caffeine or sharp fluctuations.

1. Activates AMPK โ€“ the bodyโ€™s main metabolic switch

AMPK helps cells decide when to store energy and when to use it. Dihydroberberine supports its activation, metabolic flexibility, and a more balanced use of energy in the body.

2. Supports mitochondria and ATP production

Coenzyme Q10 is directly involved in ATP production, while PQQ supports mitochondrial function and renewal. Together, they contribute to more stable energy, better endurance, and less fatigue.

3. Supports sugar and fat metabolism

Dihydroberberine helps the body work more efficiently with glucose, fats, and other nutrients. This supports metabolic balance and helps reduce energy fluctuations throughout the day.

4. Supports autophagy and cellular renewal

Glycine and AMPK activation support the bodyโ€™s natural cellular clean-up processes, in which cells recycle damaged or unnecessary components. This contributes to long-term cellular health and healthy ageing.

5. Supports NAD+, the nervous system, and recovery

Vitamin B3 is involved in NAD+ production, while vitamin B1 contributes to normal energy metabolism and the normal function of the nervous system. MitoGenix therefore connects cellular energy with both physical and mental resilience.

MitoGenix supports energy right where it is created โ€“ in the mitochondria โ€“ and helps the body function more steadily, efficiently, and without unnecessary stimulation.

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With regular use of MitoGenix, most users typically notice the onset of effects along the following timeline:

Timeline of MitoGenix effects on the body

  • Week 1:

    You may begin to notice an initial increase in energy, better focus, reduced cravings for quick sources of sugar, and more balanced functioning throughout the day.

  • Month 1:

    Energy tends to feel more stable, physical endurance improves, afternoon slumps are eased, and digestion and nutrient processing may feel more balanced.

  • 3rd month:

    Longer-term support of AMPK and mitochondria may be reflected in better metabolic flexibility, more stable glucose management, greater resilience, and faster recovery.

  • Month 6 onwards:

    Regular use supports long-term cellular energy, healthy metabolic signalling, stable vitality, and sustainable physical performance.

WHAT DO THE EXPERTS SAY

MitoGenix represents an approach grounded in available scientific evidence to support mitochondrial energy metabolism and steady everyday vitality without reliance on stimulants. This formulation uses carefully selected ingredients that have been studied in human clinical research for their role in cellular energy production, mitochondrial function, and fatigue-related outcomes. Importantly, the individual ingredients work through complementary physiological pathways within mitochondrial bioenergetics. By addressing multiple aspects of mitochondrial physiology, MitoGenix offers a scientifically credible, stimulant-free strategy to support physical energy, metabolic resilience, and everyday functional vitality.

Dr. Matt Higgins: BBA (Hons), BSc (Hons), PhD, FHEA
Dr. Matt Higgins: BBA (Hons), BSc (Hons), PhD, FHEA
Dr. Matt Higgins is an award-winning expert in human physiology and nutritional physiology. As a former associate professor and current scientific advisor, he has long been dedicated to developing dietary supplements grounded in a scientific approach. He is the author of more than 25 peer-reviewed scientific publications.

Who is this supplement intended for?

  • For professionals who need stable energy and balanced performance from morning to evening

    For professionals who need stable energy and balanced performance from morning to evening

  • For active people over 40 who want to manage work, family, and their own pace with greater ease

    For active people over 40 who want to manage work, family, and their own pace with greater ease

  • For those who notice rapid drops in energy and a slower return of vitality

    For those who notice rapid drops in energy and a slower return of vitality

  • For people seeking energy support without short-term stimulation

    For people seeking energy support without short-term stimulation

Recommended use

Daily dosage
2 capsules daily.
When to take
1 capsule in the morning and 1 capsule during the day, with a meal containing a small amount of fats (nuts, olive oil, avocado). The capsules can also be taken at the same time. No later than noon.
With or without food
Take with a meal containing fats for optimal absorption of coenzyme Q10 and PQQ.
Important
Do not exceed the recommended daily dose. Do not take in the late afternoon or evening.
Storage
Store in a dry, cool place away from direct sunlight. Food supplements are not a substitute for a varied and balanced diet and a healthy lifestyle. Best before date and batch number: see packaging.

Warning: If you are taking medication for diabetes, high blood pressure, or blood thinning, consult your doctor before use. Piperine (Bioperineยฎ) may affect the absorption of some medications.

Key benefits

  • Steady energy renewal

    Steady energy renewal

    More stable energy and vitality without unnecessary fluctuations.

    • Vitamin B3
    • Vitamin B1
    • Coenzyme Q10
  • Efficient use of nutrients

    Efficient use of nutrients

    Supports the conversion of sugars and fats into energy and contributes to more balanced digestion.

    • Dihydroberberine
    • BioPerineยฎ
    • Vitamin B1
    • Vitamin B3
Key benefits
  • Cellular vitality and protection

    Cellular vitality and protection

    Helps protect cells from damage and supports cellular energy production.

    • Coenzyme Q10
    • PQQ
  • Nervous system support

    Nervous system support

    Supports the nervous system and mental balance.

    • Vitamin B1
    • Vitamin B3
    • L-Glycine
    • Coenzyme Q10
  • Metabolic balance

    Metabolic balance

    Helps the body better manage stress and use energy more efficiently.

    • L-Glycine
    • Dihydroberberine
    • Vitamin B3
    • Vitamin B1

Thoughtful combinations for long-term vitality

By combining multiple NOZONO formulas, you can support key areas of health in a broader context and benefit from their synergistic effect. Choose a bundle according to your priorities, needs, and pace of life.
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Longevity Foundation Duo

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Metabolic Clarity Stack

Stable energy, clearer thinking, and metabolic balance

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Discover all bundles

Ingredients

MitoGenix is built on carefully selected ingredients, which support vitality and contribute to normal metabolic function. Its formulation reflects a thoughtful, long-term sustainable approach to energy, balance and everyday performance. Suitable for vegetarians.

L-Glycine

L-Glycine

Content: 1190 mg, NRV: Not established

  • A key building block of collagen
  • A natural part of the nervous system
  • Supports your recovery protocol
Dihydroberberine

Dihydroberberine

Content: 200 mg, NRV: Not established

  • Superior absorption
  • Nutrient metabolism support
  • Hormonal balance support
Coenzyme Q10

Coenzyme Q10

Content: 200 mg, NRV: Not established

  • Fuel for cellular mitochondria
  • Natural generator of energy (ATP)
  • Vitamin complex to help reduce fatigue*
PQQ (pyrroloquinoline quinone)

PQQ (pyrroloquinoline quinone)

Content: 20 mg, NRV: Not established

  • Cellular energy protection
  • Synergy with coenzyme Q10
  • Care for cellular energy
BioPerineยฎ

BioPerineยฎ

Content: 4 mg, NRV: Not established

  • Helps absorb vitamins and coenzyme Q10
  • Supports healthy digestion
  • Protects cells from damage caused by free radicals
Vitamin B3 (Niacin)

Vitamin B3 (Niacin)

Content: 50 mg, NRV: 302%

  • Contributes to normal energy-yielding metabolism
  • Supports the normal function of the nervous system
  • Contributes to the reduction of tiredness and fatigue
Vitamin B1

Vitamin B1

Content: 2 mg, NRV: 364%

  • Contributes to normal energy metabolism
  • Supports nervous system function
  • Contributes to normal heart function
Show all 25 reviews

Frequently Asked Questions

How does MitoGenix support the body?

MitoGenix brings together a thoughtful combination of dihydroberberine, vitamins B1 and B3, coenzyme Q10, and PQQ, designed to support nutrient utilization and normal energy metabolism. The formula targets the mitochondria - the bodyโ€™s main source of cellular energy - and supports steadier vitality without unnecessary dips.

Dihydroberberine helps support the bodyโ€™s natural handling of glucose, while B vitamins contribute to the conversion of nutrients into energy. Together with Q10 and PQQ, they form the foundation of a formula that supports longer-lasting energy, metabolic balance, and everyday performance without short-term stimulation.

Who benefits most from MitoGenix?

MitoGenixยฎ was created for people who expect high performance from themselves every day but do not want to rely on short-term stimulants for energy. It supports stable vitality throughout the day and, after the age of 40, may help you better manage work pace, physical strain, and the everyday demands of modern life. This leaves more energy for work, movement, family, and time for yourself. It is intended for active men and women who want to perform at their best without unnecessary fluctuations.

Can MitoGenix be combined with other supplements?

Yes, MitoGenix is compatible in most cases with standard multivitamins, magnesium, and omega-3 fatty acids. We recommend caution with products containing high levels of berberine or dihydroberberine, where there may be an undesirable overlap in effect.

When will I feel the effects?

Most users notice the first subtle changes within 5 to 7 days of regular use. A more noticeable development of the effect in the areas of metabolism, energy, and overall vitality usually occurs between weeks 4 and 8.

Why is it necessary to take 2 tablets a day?

Dividing it into two doses was chosen to support better use of DHB and a more even effect of the formula throughout the day. This routine helps maintain more stable energy from morning to evening without unnecessary fluctuations.

Is the supplement also suitable during periods of high work-related or mental stress?

Yes, B vitamins support the normal functioning of the nervous system and contribute to mental balance. The combination of coenzyme Q10 and PQQ was included in the formula to support cells during periods of increased strain, which may also help improve overall resilience to stress.

Is MitoGenix safe for long-term use?

Yes, MitoGenix is formulated to be suitable for long-term use as well. It is based on substances that naturally contribute to energy metabolism, and its formula is free from stimulants, colourings, and other unnecessary additives. If you are taking medication for diabetes or blood pressure, it is always advisable to consult your doctor beforehand.

Clinical Studies and Research

Systematic review of piperine as a bioavailability enhancer: approximately 2000% increase in serum curcumin concentration in humans ยท JDDT ยท 2022
Analysis of DHB Metabolites in the Caco-2 Model and a Human Pilot Study: DHB Is Efficiently Converted to Berberine ยท Metabolites (MDPI) ยท 2025
Dihydroberberine in a human study: 100โ€“200 mg of DHB achieved higher berberine AUC and Cmax compared with 500 mg of berberine HCl ยท Moon et al. ยท Nutrients (MDPI) ยท 2021
Glycine supplementation improves insulin sensitivity and lipid profile ยท ScienceDirect ยท 2023
Glycine therapy increases insulin sensitivity and glutathione synthesis in a model of insulin resistance ยท El-Hafidi et al. ยท 2018
Berberine derivatives: lower doses achieve a stronger effect on glycaemia and insulin sensitivity compared with conventional berberine ยท Diabetes (ADA) ยท 2008
CoQ10 supplementation increased plasma and muscle Q10 levels and reduced markers of oxidative stress ยท Cooke et al. ยท Journal of the International Society of Sports Nutrition ยท 2008
CoQ10 in middle-aged men (150 mg/day for 2 months): increased serum levels and improved exercise tolerance ยท PubMed ยท 1995
Systematic Review: CoQ10 reduces fatigue and oxidative stress, improves recovery in physically active and older adults ยท Nutrients (MDPI) ยท 2022
Niacin at a dose of 750โ€“1000 mg/day in patients with mitochondrial myopathy: significant increase in systemic NAD+ and improved muscle strength ยท Pirinen et al. ยท Cell Metabolism ยท 2020
Review: The Role of Niacin in Energy Metabolism and Cardiovascular Risk ยท Food and Nutrition Research ยท 2023
Overview of NAD+ metabolism: NAD+ levels decline with age; supplementation with NAD+ precursors shows promise for cardiometabolic health ยท Circulation (AHA) ยท 2022
Thiamine deficiency is associated with impaired glucose metabolism, diabetes, and atherosclerosis; B1 supplementation improves glycemic and lipid profiles ยท International Journal of Molecular Sciences (MDPI) ยท 2025
Systematic review of thiamine supplementation: significant improvement in cardiometabolic parameters, especially in patients with diabetes and heart failure ยท PMC ยท 2025
Randomized study of PQQ (20 mg/day for 8 weeks): reduced subjective fatigue, improved sleep parameters, reduced stress markers ยท Nakano et al. ยท Functional Foods in Health and Disease ยท 2012
Review 2021: PQQ stimulates mitochondrial biogenesis, influences cell growth and reproduction ยท FASEB Journal ยท 2021

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